Conclusion
Infusion of MOG35-55 peptide-conjugated splenocytes (MOG-SP)
can significantly prevent and reverse autoimmune encephalomyelitis (EAE).

Conclusion
The GP100-conjugated cell group significantly inhibited tumor growth, showing significant differences compared with the simple incubation group, PBS group and Alum+GP100 group (GP-100: GP100-conjugated splenocyte group).

Conclusion
The injection of antigen-protein conjugated splenocytes induces a significantly stronger antigen-specific immune response compared to vaccination with higher doses of protein-adjuvant vaccines.

(Left graph)Immune response levels:Infusion of protein-conjugated cells resulted in markedly elevated levels of rGPC3-specific antibodies, significant lymphocyte proliferation, increased CD3/CD8-positive ratios, higher IFN-γ secretion, and enhanced CTL activity.

(Right graph) Tumor tissue changes:At the end of the experiment, the average tumor size was 427.3 mm³ in the LC/GPC3+ group, 797.4 mm³ in the LC/GPC3 group, and 1072.1 mm³ in the LC group. The LC/GPC3+ treatment group demonstrated significant anti-tumor effects compared to the other treatment groups.